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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
VDAC2_HUMAN
USC-OGP 2-DE database
:
VDAC2_HUMAN
VDAC2_HUMAN
General information about the entry
View entry in simple text format
Entry name
VDAC2_HUMAN
Primary accession number
P45880
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Voltage-dependent anion-selective channel protein 2; Short=VDAC-2; Short=hVDAC2; AltName: Full=Outer mitochondrial membrane protein porin 2;.
Gene name
Name=VDAC2
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_6-11
{PLATELET 6-11}
Homo sapiens (Human)
map experimental info
PLATELET_6-11
MAP LOCATIONS:
SPOT OGP-0989
:
pI=7.07; Mw=28404
Cross-references
UniProtKB/Swiss-Prot
P45880; VDAC2_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
VDAC2_HUMAN
Primary accession number
P45880
Secondary accession number(s)
Q5VWK1 Q5VWK3 Q6IB40 Q7L3J5 Q9BWK8 Q9Y5I6
Sequence was last modified on
September 11, 2007 (version 2)
Annotations were last modified on
March 15, 2017 (version 165)
Name and origin of the protein
Description
RecName: Full=Voltage-dependent anion-selective channel protein 2; Short=VDAC-2; Short=hVDAC2; AltName: Full=Outer mitochondrial membrane protein porin 2;
Gene name
Name=VDAC2
Encoded on
Name=VDAC2
Keywords
Acetylation
;
Alternative splicing
;
Complete proteome
;
Direct protein sequencing
;
Ion transport
;
Isopeptide bond
;
Membrane
;
Mitochondrion
;
Mitochondrion outer membrane
;
NAD
;
Nucleotide-binding
;
Polymorphism
;
Porin
;
Reference proteome
;
Transmembrane
;
Transmembrane beta strand
;
Transport
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
L08666; AAA60144.1
; ALT_FRAME; mRNA
EMBL
L08666; AAA60145.1
; ALT_FRAME; mRNA
EMBL
L06328; AAB59457.1
; -; mRNA
EMBL
AF152227; AAD40241.1
; -; Genomic_DNA
EMBL
AF152220; AAD40241.1
; JOINED; Genomic_DNA
EMBL
AF152221; AAD40241.1
; JOINED; Genomic_DNA
EMBL
AF152222; AAD40241.1
; JOINED; Genomic_DNA
EMBL
AF152223; AAD40241.1
; JOINED; Genomic_DNA
EMBL
AF152224; AAD40241.1
; JOINED; Genomic_DNA
EMBL
AF152225; AAD40241.1
; JOINED; Genomic_DNA
EMBL
AF152226; AAD40241.1
; JOINED; Genomic_DNA
EMBL
CR456964; CAG33245.1
; -; mRNA
EMBL
AL390034; CAH73108.1
; -; Genomic_DNA
EMBL
AL392111; CAH73108.1
; JOINED; Genomic_DNA
EMBL
AL392111; CAI40914.1
; -; Genomic_DNA
EMBL
AL390034; CAI40914.1
; JOINED; Genomic_DNA
EMBL
AL390034; CAH73107.1
; -; Genomic_DNA
EMBL
AL392111; CAH73107.1
; JOINED; Genomic_DNA
EMBL
AL392111; CAI40911.1
; -; Genomic_DNA
EMBL
AL390034; CAI40911.1
; JOINED; Genomic_DNA
EMBL
AL390034; CAH73106.1
; ALT_SEQ; Genomic_DNA
EMBL
AL392111; CAH73106.1
; JOINED; Genomic_DNA
EMBL
AL392111; CAI40910.1
; ALT_SEQ; Genomic_DNA
EMBL
AL390034; CAI40910.1
; JOINED; Genomic_DNA
EMBL
BC000165; AAH00165.2
; -; mRNA
EMBL
BC012883; AAH12883.2
; -; mRNA
EMBL
BC072407; AAH72407.1
; -; mRNA
CCDS
CCDS53544.1; -. [P45880-1]
; .
CCDS
CCDS7348.1; -. [P45880-3]
; .
PIR
A45972; A45972
; .
PIR
B44422; B44422
; .
RefSeq
NP_001171712.1; NM_001184783.2. [P45880-1]
; .
RefSeq
NP_001171752.1; NM_001184823.1. [P45880-3]
; .
RefSeq
NP_001311017.1; NM_001324088.1. [P45880-3]
; .
RefSeq
NP_003366.2; NM_003375.4. [P45880-3]
; .
UniGene
Hs.355927; -
; .
ProteinModelPortal
P45880; -
; .
SMR
P45880; -
; .
BioGrid
113260; 129
; .
IntAct
P45880; 44
; .
MINT
MINT-3016132; -
; .
STRING
9606.ENSP00000361635; -
; .
BindingDB
P45880; -
; .
ChEMBL
CHEMBL6190; -
; .
DrugBank
DB01375; Aluminium monostearate
; .
DrugBank
DB06098; PRLX 93936
; .
TCDB
1.B.8.1.12; the mitochondrial and plastid porin (mpp) family
; .
iPTMnet
P45880; -
; .
PhosphoSitePlus
P45880; -
; .
SwissPalm
P45880; -
; .
BioMuta
VDAC2; -
; .
DMDM
158518391; -
; .
DOSAC-COBS-2DPAGE
P45880; -
; .
OGP
P45880; -
; .
REPRODUCTION-2DPAGE
P45880; -
; .
SWISS-2DPAGE
P45880; -
; .
UCD-2DPAGE
P45880; -
; .
EPD
P45880; -
; .
PaxDb
P45880; -
; .
PeptideAtlas
P45880; -
; .
PRIDE
P45880; -
; .
TopDownProteomics
P45880-3; -. [P45880-3]
; .
DNASU
7417; -
; .
Ensembl
ENST00000313132; ENSP00000361635
; ENSG00000165637. [P45880-1]; .
Ensembl
ENST00000332211; ENSP00000361686
; ENSG00000165637. [P45880-3]; .
Ensembl
ENST00000543351; ENSP00000443092
; ENSG00000165637. [P45880-3]; .
GeneID
7417; -
; .
KEGG
hsa:7417; -
; .
UCSC
uc001jwz.5; human. [P45880-3]
; .
CTD
7417; -
; .
DisGeNET
7417; -
; .
GeneCards
VDAC2; -
; .
H-InvDB
HIX0029994; -
; .
HGNC
HGNC:12672; VDAC2
; .
HPA
HPA043475; -
; .
MIM
193245; gene
; .
neXtProt
NX_P45880; -
; .
OpenTargets
ENSG00000165637; -
; .
PharmGKB
PA37295; -
; .
eggNOG
KOG3126; Eukaryota
; .
eggNOG
ENOG410ZBK1; LUCA
; .
GeneTree
ENSGT00390000011336; -
; .
HOVERGEN
HBG054036; -
; .
InParanoid
P45880; -
; .
KO
K15040; -
; .
OMA
MCVPPSY; -
; .
OrthoDB
EOG091G0F0O; -
; .
PhylomeDB
P45880; -
; .
TreeFam
TF315091; -
; .
Reactome
R-HSA-5689880; Ub-specific processing proteases
; .
GeneWiki
VDAC2; -
; .
GenomeRNAi
7417; -
; .
PRO
PR:P45880; -
; .
Proteomes
UP000005640; Chromosome 10
; .
Bgee
ENSG00000165637; -
; .
CleanEx
HS_VDAC2; -
; .
ExpressionAtlas
P45880; baseline and differential
; .
Genevisible
P45880; HS
; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0045121; C:membrane raft
; IDA:UniProtKB; .
GO
GO:0005743; C:mitochondrial inner membrane
; IEA:Ensembl; .
GO
GO:0042645; C:mitochondrial nucleoid
; IDA:BHF-UCL; .
GO
GO:0005741; C:mitochondrial outer membrane
; IEA:UniProtKB-SubCell; .
GO
GO:0005739; C:mitochondrion
; IDA:UniProtKB; .
GO
GO:0043209; C:myelin sheath
; IEA:Ensembl; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0046930; C:pore complex
; IEA:UniProtKB-KW; .
GO
GO:0008021; C:synaptic vesicle
; IEA:Ensembl; .
GO
GO:0000166; F:nucleotide binding
; IEA:UniProtKB-KW; .
GO
GO:0015288; F:porin activity
; IEA:UniProtKB-KW; .
GO
GO:0008308; F:voltage-gated anion channel activity
; IDA:UniProtKB; .
GO
GO:0006820; P:anion transport
; IDA:UniProtKB; .
GO
GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway
; IEA:Ensembl; .
GO
GO:0032272; P:negative regulation of protein polymerization
; IEA:Ensembl; .
Gene3D
2.40.160.10; -
; 1; .
InterPro
IPR023614; Porin_dom
; .
InterPro
IPR001925; Porin_Euk
; .
InterPro
IPR027246; Porin_Euk/Tom40
; .
Pfam
PF01459; Porin_3
; 1; .
PRINTS
PR00185; EUKARYTPORIN
; .
PROSITE
PS00558; EUKARYOTIC_PORIN
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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